Lupus research, hydroxychloroquine and cardiovascular heart healthNews

New Lupus Research Highlights Heart Health

New research is offering another important reason for people living with lupus to have informed conversations with their healthcare providers about taking prescribed medications consistently.

A recent study examined the relationship between hydroxychloroquine (HCQ)—one of the most widely used treatments for systemic lupus erythematosus (SLE)—and cardiovascular risk. Researchers studied 248 adults with lupus, looking at hydroxychloroquine blood levels and longer-term medication use.

The researchers found that patients with very low HCQ blood levels and low long-term medication intake had higher estimated cardiovascular risk than patients with greater exposure to the medication. The findings add to growing research examining the relationship between lupus treatment and long-term heart health.

Why Heart Health Matters in Lupus

Lupus is a complex autoimmune disease that can affect many parts of the body, including the cardiovascular system. Understanding and managing cardiovascular risk can therefore be an important part of long-term lupus care.

Hydroxychloroquine has long been a foundational treatment for many people living with lupus. The new research provides another reason for patients and healthcare providers to discuss medication adherence, appropriate monitoring and cardiovascular health as part of an individualized treatment plan.

Turning Research Into Better Patient Conversations

Medication decisions should always be made in consultation with a qualified healthcare professional. Patients should not begin, stop or change the dosage of hydroxychloroquine—or any medication—based solely on the results of a research study.

At The Reid Foundation for Lupus®, we believe access to credible, understandable information can help people affected by lupus become better informed and more engaged in their healthcare. As research continues to advance our understanding of this complex disease, we will continue sharing developments that matter to the lupus community.

Source: Arthritis Care & Research / Yale School of Medicine.

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LUPKYNIS Continues to Show Promising Lupus Nephritis Outcomes

The drug treatment, LUPKYNIS® (voclosporin), reduced inflammation and prevented development of kidney damage in people with lupus nephritis (LN, lupus-related kidney disease) over 18 months. Those taking the medication also didn’t exhibit any signs of kidney-related toxicity. LUPKYINS® is a novel, structurally modified calcineurin inhibitor (CNI) that works in two ways – acting as an immunosuppressant through inhibition of T-cell activation and cytokine production, and by promoting podocyte stability in the kidney.

 

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Article Credit: Lupus Foundation of America | lupus.org

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Congratulations to Our Board Members

Congratulations to our board members, Dr. Sam Lim, Georgia State Rep. Kim Schofield and Founder Bryant Reid for being named Community Service awardees at the Phenomenal Women’s Health Annual Fundraising Tea.

 

(Pictured in the photo above l to r: Kim Schofield – Georgia State Representative, Teri Edmond – CEO of Lupus Foundation of America Georgia Chapter, Cheryl Burnside – CEO of Phenomenal Women’s Health, Bryant Reid – President of The Reid Foundation For Lupus, Inc.)

 

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In People with Lupus, Age and Location Linked to Delayed Follow-Up After Hospitalization

March 30, 2023

Research shows younger people living with lupus and those living in rural or disadvantaged areas are less likely to have a follow-up appointment with their doctor shortly after they’ve been discharged from the hospital. One quarter of people with lupus are hospitalized every year, and one-third are re-hospitalized within 30 days, underscoring the importance of timely outpatient care.

Looking at data from 8,606 adults hospitalized with lupus on Medicare, researchers found that 35% lacked follow-up within 30 days overall. That follow-up rate is worse than the rate reported among people with other chronic diseases.

People with lupus who also exhibited the following characteristics were less likely to have a timely follow-up appointment after hospital discharge:

  • More co-occurring illnesses
  • A longer hospital length-of-stay
  • Rural place of residency
  • Greater neighborhood disadvantage

In the 65 years and older cohort, receiving timely follow-up care was associated with a 65% lower mortality rate in the month following hospital discharge, highlighting the tremendous value of outpatient treatment in this population in particular.

Regular preventative and follow-up care is critically important to living well with lupus, yet many struggle to get the medical support they need. Learn more about barriers to lupus diagnosis and care.

 

Article Credit: Lupus Foundation of America | lupus.org

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