News

Clinical Trial for New Lupus Treatment Opens in China

April 23, 2023

JW Therapeutics has received approval from the National Medical Products Administration of China to conduct a Phase 1 / 2 clinical trial of its CAR T-cell therapy, relmacabtagene autoleucel (relma-cel), for people with moderate to severe and/or treatment-resistant lupus. CAR T-cells are genetically altered T-cells that play a role in the immune response. Scientists create or engineer new cells called chimeric antigen receptors (CARs), and then introduce T-cells into them to create CAR-T cells.

 

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Article Credit: Lupus Foundation of America | lupus.org

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News

RINVOQ Advances to Phase 3 Clinical Trials for Lupus Treatment

April 3, 2023

March 27, 2023

AbbVie announced that its drug therapy upadacitinib (also known as RINVOQ®) is entering Phase 3 clinical trial for treatment of lupus. RINVOQ is already approved for the treatment of other autoimmune conditions, such as rheumatoid arthritis, psoriatic arthritis, and eczema.

In the M19-130 Phase 2 trial of RINVOQ, the drug met its primary endpoint either given alone or as a combination therapy to people with moderately or severely active lupus disease. The drug was given to five groups, a total of 341 people, and none of the trial participants exhibited any new safety issues with the treatment.

Continue to follow the Lupus Foundation of America for updates on RINVOQ as well as other lupus clinical trials.

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Article Credit: Lupus Foundation of America | lupus.org

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